Synthesis of Heterocyclic Skeletons by the Reaction of N-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides
نویسنده
چکیده
The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyland diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5benzotriazocine and quinazoline. The reaction pathways of prepared compounds are discussed.
منابع مشابه
One-Pot Quinazolin-4-ylidenethiourea Synthesis via N-(2- Cyanophenyl)benzimidoyl isothiocyanate
1,1-Disubstituted-3-(2-phenyl-3H-quinazolin-4-ylidene)thioureas (8) were synthesized in a one pot reaction of N-(2-cyanophenyl)benzimidoyl isothicyanate (3) with secondary amines. The products underwent transamination reactions. Compounds 8a-8g were identified by FTIR, H-NMR, C-NMR, mass spectroscopy and X-ray crystallography.
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